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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIFR
All Species:
10.61
Human Site:
Y379
Identified Species:
25.93
UniProt:
P42702
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42702
NP_001121143.1
1097
123743
Y379
V
E
S
F
S
G
K
Y
V
R
L
K
R
A
E
Chimpanzee
Pan troglodytes
XP_001141959
1097
123652
Y379
V
E
S
F
S
G
K
Y
V
R
L
K
R
A
E
Rhesus Macaque
Macaca mulatta
XP_001082842
1083
122228
P374
R
F
K
R
A
E
A
P
T
N
G
S
Y
Q
L
Dog
Lupus familis
XP_546341
967
108830
W291
K
H
K
S
W
C
N
W
Q
V
A
S
E
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
P42703
1092
122555
S374
F
E
S
I
S
G
K
S
A
V
F
H
R
I
E
Rat
Rattus norvegicus
O70535
1093
122376
S375
F
E
S
I
S
G
K
S
A
V
F
H
R
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507581
966
108440
T290
N
P
L
G
R
S
E
T
S
V
L
V
D
I
T
Chicken
Gallus gallus
NP_989906
1083
120845
H373
V
N
E
M
K
K
K
H
V
C
G
F
P
V
L
Frog
Xenopus laevis
NP_001124412
881
98985
T205
L
G
I
Q
K
S
E
T
L
T
I
D
P
V
N
Zebra Danio
Brachydanio rerio
NP_001014328
929
102512
R253
R
L
K
K
R
N
S
R
T
N
Y
T
L
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95.8
29
N.A.
75.2
74.1
N.A.
61.3
52.2
20.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.9
97.4
45.5
N.A.
85.5
84.9
N.A.
72.5
70
37.1
43.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
46.6
46.6
N.A.
6.6
20
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
20
N.A.
46.6
46.6
N.A.
13.3
26.6
26.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
20
0
10
0
0
20
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% D
% Glu:
0
40
10
0
0
10
20
0
0
0
0
0
10
0
40
% E
% Phe:
20
10
0
20
0
0
0
0
0
0
20
10
0
10
0
% F
% Gly:
0
10
0
10
0
40
0
0
0
0
20
0
0
0
10
% G
% His:
0
10
0
0
0
0
0
10
0
0
0
20
0
0
0
% H
% Ile:
0
0
10
20
0
0
0
0
0
0
10
0
0
20
0
% I
% Lys:
10
0
30
10
20
10
50
0
0
0
0
20
0
0
0
% K
% Leu:
10
10
10
0
0
0
0
0
10
0
30
0
10
0
20
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
10
10
0
0
20
0
0
0
10
10
% N
% Pro:
0
10
0
0
0
0
0
10
0
0
0
0
20
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
10
0
0
0
0
10
10
% Q
% Arg:
20
0
0
10
20
0
0
10
0
20
0
0
40
0
0
% R
% Ser:
0
0
40
10
40
20
10
20
10
0
0
20
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
20
20
10
0
10
0
0
10
% T
% Val:
30
0
0
0
0
0
0
0
30
40
0
10
0
20
0
% V
% Trp:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
20
0
0
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _